Soil Enzymatic Activities and Microbial Community Structure in Soils Polluted with Tetracycline Antibiotics

A laboratory experiment was performed to examine the medium-term influence of three tetracycline antibiotics (chlortetracycline, CTC; tetracycline, TC and oxytetracycline, OTC) at different concentrations in four agricultural soils with similar pH soil organic content. After a 42-days incubation period, enzymes (?-glucosidase, urease, phosphomonoesterase) were estimated, as well phospholipid fatty acids (PLFAs). residual effect observed on all microbial parameters measured affecting activity communities structure (PLFA pattern). sensitivity detected depending both, type property considered. Specifically, general, no antibiotic or even slight positive for phosphomonoesterase ?-glucosidase enzyme activities, respectively, while negative urease values, particularly higher doses low matter The principal component analysis PLFAs data obtained samples showed mainly type, followed by added (CTC, and, lesser extent, its concentration. In PLFA patterns due OTC addition comparison treated CTC. These results could be environmentally relevant, especially regards potential effects microbiome hence health risk assessment these soils.